Influenza Virus Polymerase Mutation Stabilizes a Foreign Gene Inserted into the Virus Genome by Enhancing the Transcription/Replication Efficiency of the Modified Segment - Furusawa, Yuri; Yamada, Shinya; da Silva Lopes, Tiago Jose; Dutta, Jayeeta; Khan, Zenab; Kriti, Divya; van Bakel, Harm; Kawaoka, Yoshihiro (mBio, 2019)
Keywords: Animals; Bacterial Proteins - genetics; Dogs; foreign gene insertion; genetic stability; Genome, Viral; Genomic Instability; HEK293 Cells; Host-Microbe Biology; Humans; influenza; Influenza A Virus, H1N1 Subtype - genetics; Influenza A Virus, H5N1 Subtype - genetics; Interferon-beta - genetics; Luminescent Proteins - genetics; Madin Darby Canine Kidney Cells; Mutagenesis, Insertional; Mutation; Real-Time Polymerase Chain Reaction; recombinant virus; RNA, Viral - genetics; Transcription, Genetic; virus polymerase; Virus Replication; influenza; recombinant virus; genetic stability; foreign gene insertion; virus polymerase