MicroRNA-34c-5p exhibits anticancer properties in gastric cancer by targeting MAP2K1 to inhibit cell proliferation, migration, and invasion

• Published in: BioMed research international Vol. 2022; no. 1; p. 7375661
• Main Authors: Ma, Qian, Zhao, Yuan, Li, Zhaojun, Gao, Wenwei, Xu, Yuanyi, Li, Bing, Huang, Yunning, Huo, Zhenghao
• Format: Journal Article
• Language: English
• Published: New York Hindawi 2022; John Wiley & Sons, Inc
• Subjects: Antibodies; Anticancer properties; Binding sites; Bioinformatics; Biomarkers; Cancer; Care and treatment; Cell culture; Cell growth; Cell migration; Cell proliferation; Cloning; E-cadherin; Gastric cancer; Gastrointestinal tract; Genetic aspects; Health aspects; Medical prognosis; Medical research; Membranes; MicroRNA; MicroRNAs; miRNA; Mitogen-activated protein kinases; N-Cadherin; Oncology, Experimental; Pathogenesis; Proteins; Reagents; Stomach cancer; Therapeutic targets; Tumors; Vimentin; Wound healing; China; Beijing China; Israel; United States > US; Japan

Purpose. Gastric cancer(GC)is one of the deadliest digestive tract tumors worldwide，existing studies suggest that dysregulated expression of microRNAs (miRNAs) plays an important role in the pathogenesis and progression of GC. This study aimed to investigate the expression, biological function, and...