A coordinate-based meta-analysis of the n-back working memory paradigm using activation likelihood estimation

• Published in: Brain and cognition Vol. 132; pp. 1 - 12
• Main Authors: Wang, Hui, He, Weijiang, Wu, Jingting, Zhang, Junjun, Jin, Zhenlan, Li, Ling
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.2019; Elsevier Science
• Subjects: Anterior insula (aI); Brain - diagnostic imaging; Brain - physiology; Cerebral Cortex - diagnostic imaging; Cerebral Cortex - physiology; Chinese languages; Cortex (parietal); Frontal cortex; Frontal gyrus; Frontal Lobe - diagnostic imaging; Frontal Lobe - physiology; Functional Neuroimaging; Humans; Likelihood Functions; Magnetic Resonance Imaging; Memory, Short-Term - physiology; Mental task performance; Meta-analysis; N-back task; Neuroimaging; Parietal cortex; Parietal Lobe - diagnostic imaging; Parietal Lobe - physiology; Prefrontal Cortex - diagnostic imaging; Prefrontal Cortex - physiology; Quantitative meta-analysis; Short term memory; Task Performance and Analysis; Thalamus; Thalamus - diagnostic imaging; Thalamus - physiology; Working memory; N-back task; Quantitative meta-analysis; Working memory; Frontal cortex; Anterior insula (aI); Parietal cortex

•Data was pooled from 96 studies of n-back (120 experiments and 2846 subjects).•The results showed consistent activation of the frontal-parietal cortices and aI.•Compared with 1-back, 2-back increased activation in left MFG, left IFG and left aI.•Compared with object location, object identity increa...