Cerebrospinal fluid markers of inflammation and brain injury in Lyme neuroborreliosis – a prospective follow-up study

• Published in: Clinical chemistry and laboratory medicine Vol. 60; no. 7; pp. 1124 - 1132
• Main Authors: Tjernberg, Ivar, Gyllemark, Paula, Zetterberg, Henrik, Blennow, Kaj, Ernerudh, Jan, Forsberg, Pia, Sjöwall, Johanna, Henningsson, Anna J.
• Format: Journal Article
• Language: English
• Published: Germany De Gruyter 27.06.2022; Walter De Gruyter & Company
• Subjects: Anesthesia; Antibiotics; biomarkers; Borreliosis; Brain; Brain injury; Central nervous system; Cerebrospinal fluid; CXCL13 protein; Diagnosis; Differential diagnosis; Glial fibrillary acidic protein; Head injuries; Inflammation; Lyme disease; Lyme neuroborreliosis; Markers; Myeloid cells; Neuronal-glial interactions; Neurosciences; Neurovetenskaper; pathogenesis; Patients; Proteins; Tau protein; Traumatic brain injury; pathogenesis; brain injury; Lyme neuroborreliosis; biomarkers; cerebrospinal fluid

The purpose of this study was to evaluate levels and kinetics of cerebrospinal fluid (CSF) markers of inflammation and brain injury in patients with Lyme neuroborreliosis (LNB). Adult patients with clinically suspected LNB were enrolled, in a prospective clinical study in the South East of Sweden. P...