Dynamics of Human Gut Microbiota and Short-Chain Fatty Acids in Response to Dietary Interventions with Three Fermentable Fibers

• Published in: mBio Vol. 10; no. 1
• Main Authors: Baxter, Nielson T., Schmidt, Alexander W., Venkataraman, Arvind, Kim, Kwi S., Waldron, Clive, Schmidt, Thomas M.
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 29.01.2019
• Subjects: Adolescent; Adult; bifidobacteria; Biostatistics; butyrate; Chemistry Techniques, Analytical; Cichorium intybus; Dietary Fiber - administration & dosage; Fatty Acids, Volatile - metabolism; Feces - chemistry; Feces - microbiology; Gastrointestinal Microbiome - drug effects; Host-Microbe Biology; Humans; Inulin - administration & dosage; Metagenomics; microbiome; prebiotic; Ruminococcus; SCFA; Solanum tuberosum; Starch - administration & dosage; Young Adult; Zea mays; Ruminococcus; bifidobacteria; prebiotic; butyrate; SCFA; microbiome

These results reveal that not all fermentable fibers are equally capable of stimulating SCFA production, and they highlight the importance of the composition of an individual’s microbiota in determining whether or not they respond to a specific dietary supplement. In particular, R. bromii or C. char...