High-Resolution Adaptive Optics Retinal Imaging of Cellular Structure in Choroideremia

• Published in: Investigative ophthalmology & visual science Vol. 55; no. 10; pp. 6381 - 6397
• Main Authors: Morgan, Jessica I. W., Han, Grace, Klinman, Eva, Maguire, William M., Chung, Daniel C., Maguire, Albert M., Bennett, Jean
• Format: Journal Article
• Language: English
• Published: United States The Association for Research in Vision and Ophthalmology 10.10.2014
• Subjects: Adolescent; Adult; Cellular Structures; Child; Choroideremia - diagnosis; Choroideremia - physiopathology; Diagnostic Techniques, Ophthalmological - instrumentation; Equipment Design; Fluorescein Angiography - instrumentation; Follow-Up Studies; Fundus Oculi; Humans; Middle Aged; Ophthalmoscopes; Ophthalmoscopy - methods; Optics and Photonics; Reproducibility of Results; Retinal Cone Photoreceptor Cells - pathology; Tomography, Optical Coherence - instrumentation; Visual Acuity; Young Adult; photoreceptors; adaptive optics; retinal pigment epithelium; choroideremia

We characterized retinal structure in patients and carriers of choroideremia using adaptive optics and other high resolution modalities. A total of 57 patients and 18 carriers of choroideremia were imaged using adaptive optics scanning light ophthalmoscopy (AOSLO), optical coherence tomography (OCT)...