White matter and cognition: making the connection

• Published in: Journal of neurophysiology Vol. 116; no. 5; pp. 2093 - 2104
• Main Authors: Filley, Christopher M., Fields, R. Douglas
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.11.2016
• Series: Glial Cells and Neuronal Signaling
• Subjects: Animals; Call for Papers; Cognition - physiology; Humans; Nerve Net - diagnostic imaging; Nerve Net - physiology; Neural Pathways - diagnostic imaging; Neural Pathways - physiology; White Matter - diagnostic imaging; White Matter - physiology; myelin; glial cells; white matter; dementia; cognition

Whereas the cerebral cortex has long been regarded by neuroscientists as the major locus of cognitive function, the white matter of the brain is increasingly recognized as equally critical for cognition. White matter comprises half of the brain, has expanded more than gray matter in evolution, and f...