The PGRS Domain of Mycobacterium tuberculosis PE_PGRS Protein Rv0297 Is Involved in Endoplasmic Reticulum Stress-Mediated Apoptosis through Toll-Like Receptor 4 - Grover, Sonam; Sharma, Tarina; Singh, Yadvir; Kohli, Sakshi; P., Manjunath; Singh, Aditi; Semmler, Torsten; Wieler, Lothar H.; Tedin, Karsten; Ehtesham, Nasreen Z.; Hasnain, Seyed E. (mBio, 2018)
Keywords: Animals; Antigens, Bacterial - chemistry; Antigens, Bacterial - genetics; Antigens, Bacterial - metabolism; Antigens, Bacterial - pharmacology; Apoptosis - drug effects; Bacterial Proteins - chemistry; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Bacterial Proteins - pharmacology; calcium homeostasis; Endoplasmic Reticulum - metabolism; Endoplasmic Reticulum Stress - drug effects; ER localization signal; granulomas; HEK293 Cells; Host-Pathogen Interactions; Humans; Macrophages - cytology; Macrophages - metabolism; Macrophages - microbiology; Membrane Proteins - chemistry; Membrane Proteins - genetics; Membrane Proteins - metabolism; Membrane Proteins - pharmacology; Mice; Mycobacterium tuberculosis - pathogenicity; Mycobacterium tuberculosis - physiology; Protein Binding; Protein Sorting Signals; RAW 264.7 Cells; Toll-Like Receptor 4 - genetics; Toll-Like Receptor 4 - metabolism; unfolded protein response; Unfolded Protein Response - drug effects; unfolded protein response; calcium homeostasis; ER localization signal; granulomas