Identification of Klebsiella capsule synthesis loci from whole genome data

• Published in: Microbial genomics Vol. 2; no. 12; p. e000102
• Main Authors: Wyres, Kelly L., Wick, Ryan R., Gorrie, Claire, Jenney, Adam, Follador, Rainer, Thomson, Nicholas R., Holt, Kathryn E.
• Format: Journal Article
• Language: English
• Published: England Microbiology Society 01.12.2016
• Subjects: Bacterial Capsules - genetics; Genome, Bacterial - genetics; Klebsiella Infections - microbiology; Klebsiella pneumoniae - genetics; Research Paper; Software; Klebsiella capsule K-locus genomic surveillance

Klebsiella pneumoniae is a growing cause of healthcare-associated infections for which multi-drug resistance is a concern. Its polysaccharide capsule is a major virulence determinant and epidemiological marker. However, little is known about capsule epidemiology since serological typing is not widel...