Functions of estrogen and estrogen receptor signaling on skeletal muscle

• Published in: The Journal of steroid biochemistry and molecular biology Vol. 191; p. 105375
• Main Authors: Ikeda, Kazuhiro, Horie-Inoue, Kuniko, Inoue, Satoshi
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.07.2019; Elsevier BV
• Subjects: Estrogen; Exercise endurance; Gene regulation; Homeostasis; Menstrual cycle; Metabolic syndrome; Metabolism; Mitochondria; Molecular modelling; Musculoskeletal system; Osteoporosis; Post-menopause; Reproductive organs; Sarcopenia; Skeletal muscle; NCoA1; Rcan1; PGC1α; TIF2; Gene regulation; N-CoR; Estrogen; Exercise endurance; AIB1; pCIP; TRAP; NRF1; Skeletal muscle; CBP; PINK1; Mitochondria; GRIP; DRIP; PPT; SMRT; MuRF-1; ACTR; SRC-1

•Estrogen plays a crucial role in skeletal muscle homeostasis and exercise capacity.•Estrogen decrease may associate with sarcopenia and frailty in postmenopausal women.•Estrogen maintains mitochondrial function and metabolism in female muscle.•Estrogen improves exercise endurance and mitochondrial...