Chromosomal aberrations, sister chromatid exchanges, and urinary thioethers in nurses handling antineoplastic drugs

• Published in: American journal of industrial medicine Vol. 18; no. 6; p. 689
• Main Authors: Sarto, F, Trevisan, A, Tomanin, R, Canova, A, Fiorentino, M
• Format: Journal Article
• Language: English
• Published: United States 1990
• Subjects: Antineoplastic Agents - adverse effects; Chromosome Aberrations; Humans; Nurses; Occupational Exposure; Sister Chromatid Exchange; Sulfides - urine

In this study we examined the structural chromosomal aberrations (CA) and sister chromatid exchanges (SCE) of 12 nurses handling moderate quantities of antineoplastic drugs. Urinary thioethers were also measured to assess the potential exposure to alkylating drugs. Two control groups with similar me...