Retrobulbar Injection of Amphotericin B in Patients With COVID-19 Associated Orbital Mucormycosis: A Systematic Review

• Published in: Ophthalmic plastic and reconstructive surgery Vol. 38; no. 5; p. 425
• Main Authors: Sharifi, Ali, Akbari, Zahra, Shafie'ei, Mohammad, Nasiri, Naser, Sharifi, Meraj, Shafiei, Mohadeseh, Zand, Amin
• Format: Journal Article
• Language: English
• Published: United States 01.09.2022
• Subjects: Amphotericin B - therapeutic use; Antifungal Agents - therapeutic use; COVID-19; Eye Diseases; Eye Infections, Fungal - diagnosis; Eye Infections, Fungal - drug therapy; Humans; Mucormycosis - diagnosis; Mucormycosis - drug therapy; Orbital Diseases - diagnosis; Orbital Diseases - drug therapy; Orbital Diseases - etiology; Paranasal Sinus Diseases - diagnosis

Following COVID-19 infection a rising count of rhino-orbito-cerebral mucormycosis is observed, requiring orbital exenteration, a disabling lifetime affecting surgery. One of the potential interventions for globe salvage in these patients is retrobulbar injections of amphotericin B. This study was co...