Comparative Efficacy of 6 Topical Pharmacological Agents for Preventive Interventions of Postoperative Sore Throat After Tracheal Intubation: A Systematic Review and Network Meta-analysis

• Published in: Anesthesia and analgesia Vol. 133; no. 1; pp. 58 - 67
• Main Authors: Wang, Ge, Qi, Yang, Wu, LiNa, Jiang, GuiChun
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkin 01.07.2021
• Subjects: Administration, Topical; Airway Extubation - adverse effects; Airway Extubation - trends; Anesthetics, Local - administration & dosage; Anti-Inflammatory Agents, Non-Steroidal - administration & dosage; Humans; Intubation, Intratracheal - adverse effects; Intubation, Intratracheal - trends; Meta Analysis; Pain, Postoperative - etiology; Pain, Postoperative - prevention & control; Pharyngitis - etiology; Pharyngitis - prevention & control; Randomized Controlled Trials as Topic - methods; Review; Treatment Outcome

Topical pharmacological agents typically used to treat postoperative sore throat (POST) after tracheal intubation include nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, lidocaine, Glycyrrhiza (licorice), and N-methyl-d-aspartate (NMDA) receptor antagonists (including ketamine and ma...