Severe Acute Respiratory Syndrome Coronavirus 2 Convalescent Plasma Versus Standard Plasma in Coronavirus Disease 2019 Infected Hospitalized Patients in New York: A Double-Blind Randomized Trial

• Published in: Critical care medicine Vol. 49; no. 7; p. 1015
• Main Authors: Bennett-Guerrero, Elliott, Romeiser, Jamie L, Talbot, Lillian R, Ahmed, Tahmeena, Mamone, Linda J, Singh, Sunitha M, Hearing, Janet C, Salman, Huda, Holiprosad, Dishaw D, Freedenberg, Alex T, Carter, Jason A, Browne, Nicholas J, Cosgrove, Megan E, Shevik, Margaret E, Generale, Laura M, Andrew, Margaret A, Nachman, Sharon, Fries, Bettina C
• Format: Journal Article
• Language: English
• Published: United States 01.07.2021
• Subjects: Aged; Antibodies, Neutralizing - blood; COVID-19 - therapy; COVID-19 Serotherapy; Double-Blind Method; Female; Humans; Immunization, Passive; Immunoglobulin G - blood; Immunoglobulin M - blood; Male; Middle Aged; New York - epidemiology; SARS-CoV-2; Treatment Outcome; New York
• ISSN: 1530-0293
• DOI: 10.1097/CCM.0000000000005066

Four peer-reviewed publications have reported results from randomized controlled trials of convalescent plasma for coronavirus disease 2019 infection; none were conducted in the United States nor used standard plasma as a comparator. To determine if administration of convalescent plasma to patients...