Improving plant C-to-G base editors with a cold-adapted glycosylase and TadA-8e variants - Jiang, Yingli; Xiao, Zhi; Luo, Zhaopeng; Zhou, Suhuai; Tong, Chaoyun; Jin, Shan; Liu, Xiaoshuang; Qin, Ruiying; Xu, Rongfang; Pan, Lang; Li, Juan; Wei, Pengcheng (Trends in biotechnology (Regular ed.), 2025)
Keywords: Adenine; Animals; base editing; Cold Temperature; CRISPR; CRISPR-Cas Systems; Cytidine Deaminase - genetics; Cytidine Deaminase - metabolism; Cytosine; Cytosine - metabolism; DNA glycosylase; Editing; Efficiency; Enzymes; Gene Editing - methods; Gene sequencing; Genomic analysis; Glycosylation; Guanine - metabolism; Humans; Internal Medicine; Mutation; Oryza - genetics; Plant breeding; plants; Plants, Genetically Modified - genetics; Proteins; Soybeans; TadA variants; Tobacco; UNG; Uracil; Uracil-DNA glycosidase; Uracil-DNA Glycosidase - genetics; Uracil-DNA Glycosidase - metabolism; Whole genome sequencing; TadA variants; CRISPR; base editing; plants; UNG