PARP3 Affects Nucleosome Compaction Regulation

• Published in: International journal of molecular sciences Vol. 24; no. 10; p. 9042
• Main Authors: Ukraintsev, Alexander, Kutuzov, Mikhail, Belousova, Ekaterina, Joyeau, Marie, Golyshev, Victor, Lomzov, Alexander, Lavrik, Olga
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 20.05.2023; MDPI
• Subjects: Atomic force microscopy; Chromatin; Communication; DNA - chemistry; DNA Damage; DNA Repair; Genetic transcription; Localization; Nucleosomes; Poly (ADP-Ribose) Polymerase-1 - genetics; Poly (ADP-Ribose) Polymerase-1 - metabolism; Proteins; nucleosome; chromatin structure; atomic force microscopy; DNA compaction; poly(ADP-ribose)polymerase
• ISSN: 1422-0067; 1661-6596; 1422-0067
• DOI: 10.3390/ijms24109042

Genome compaction is one of the important subject areas for understanding the mechanisms regulating genes’ expression and DNA replication and repair. The basic unit of DNA compaction in the eukaryotic cell is the nucleosome. The main chromatin proteins responsible for DNA compaction have already bee...