Hepatitis B virus genotypes
Eight genotypes of hepatitis B virus (A–H) are currently recognized, and subgenotypes have recently been described in four of these genotypes (A, B, C and F). The genotypes show a distinct geographical distribution between and even within regions, and are proving to be an invaluable tool in tracing...
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| Published in | Vaccine Vol. 23; no. 19; pp. 2409 - 2423 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
Oxford
Elsevier Ltd
31.03.2005
Elsevier Elsevier Limited |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Eight genotypes of hepatitis B virus (A–H) are currently recognized, and subgenotypes have recently been described in four of these genotypes (A, B, C and F). The genotypes show a distinct geographical distribution between and even within regions, and are proving to be an invaluable tool in tracing the molecular evolution and patterns and modes of spread of hepatitis B virus. Structural and functional differences between genotypes can influence the severity, course and likelihood of complications, and response to treatment of hepatitis B virus infection and possibly vaccination against the virus. Although the number of studies on these genotypes has increased dramatically during recent years, much remains to be learnt about their full implications. |
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| AbstractList | Eight genotypes of hepatitis B virus (A-H) are currently recognized, and subgenotypes have recently been described in four of these genotypes (A, B, C and F). The genotypes show a distinct geographical distribution between and even within regions, and are proving to be an invaluable tool in tracing the molecular evolution and patterns and modes of spread of hepatitis B virus. Structural and functional differences between genotypes can influence the severity, course and likelihood of complications, and response to treatment of hepatitis B virus infection and possibly vaccination against the virus. Although the number of studies on these genotypes has increased dramatically during recent years, much remains to be learnt about their full implications. |
| Author | François, Guido Kew, Michael Kramvis, Anna |
| Author_xml | – sequence: 1 givenname: Anna surname: Kramvis fullname: Kramvis, Anna email: kramvisa@medicine.wits.ac.za organization: MRC/University Molecular Hepatology Research Unit, Department of Medicine, University of the Witwatersrand Medical School, 7 York Road, Parktown, 2193 Johannesburg, South Africa – sequence: 2 givenname: Michael surname: Kew fullname: Kew, Michael organization: MRC/University Molecular Hepatology Research Unit, Department of Medicine, University of the Witwatersrand Medical School, 7 York Road, Parktown, 2193 Johannesburg, South Africa – sequence: 3 givenname: Guido surname: François fullname: François, Guido organization: WHO Collaborating Centre for Prevention and Control of Viral Hepatitis, Department of Epidemiology and Social Medicine, University of Antwerp, Universiteitplein 1, B-2610 Antwerpen, Belgium |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17589151$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/15752827$$D View this record in MEDLINE/PubMed |
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| ContentType | Journal Article |
| Copyright | 2004 Elsevier Ltd 2006 INIST-CNRS Copyright Elsevier Limited Mar 31, 2005 |
| Copyright_xml | – notice: 2004 Elsevier Ltd – notice: 2006 INIST-CNRS – notice: Copyright Elsevier Limited Mar 31, 2005 |
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| DOI | 10.1016/j.vaccine.2004.10.045 |
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| Snippet | Eight genotypes of hepatitis B virus (A–H) are currently recognized, and subgenotypes have recently been described in four of these genotypes (A, B, C and F).... Eight genotypes of hepatitis B virus (A-H) are currently recognized, and subgenotypes have recently been described in four of these genotypes (A, B, C and F).... |
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| SubjectTerms | Animals Applied microbiology Biological and medical sciences Evolution Evolution, Molecular Fundamental and applied biological sciences. Psychology Genomes Genotype Genotype & phenotype Genotypes Geographical distribution Hepatitis Hepatitis B Hepatitis B - virology Hepatitis B virus Hepatitis B virus - classification Hepatitis B virus - genetics Humans Microbiology Miscellaneous Molecular Epidemiology Mutation Phylogeny Proteins Recombination Serotypes Subgenotypes Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Virology Viruses |
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| Title | Hepatitis B virus genotypes |
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