Duplicated zinc finger protein genes on the proximal short arm of the human X chromosome: isolation, characterization and X-inactivation studies

• Published in: Human molecular genetics Vol. 2; no. 10; p. 1611
• Main Authors: Greig, G M, Sharp, C B, Carrel, L, Willard, H F
• Format: Journal Article
• Language: English
• Published: England 01.10.1993
• Subjects: Amino Acid Sequence; Animals; Base Sequence; Consensus Sequence; DNA, Complementary - genetics; Dosage Compensation, Genetic; Gene Expression; Genes; Humans; Mammals - genetics; Molecular Sequence Data; Multigene Family; Organ Specificity; Sequence Alignment; Sequence Homology; Species Specificity; X Chromosome; Zinc Fingers - genetics

Two highly similar zinc finger genes, ZXDA (Zinc finger, X-linked, Duplicated) and ZXDB, have been isolated and characterized. Both map to the proximal short arm region of the human X chromosome, near locus DXS422 in Xp11.21. Both genes are expressed in several human tissues, revealing a approximate...