The Association of the R563Q Genotype of the ENaC With Phenotypic Variation in Southern Africa - Jones, Erika S.W.; Owen, E. Patricia; Rayner, Brian L. (American journal of hypertension, 2012)
Keywords: Adult; African Continental Ancestry Group - genetics; Aged; Amiloride - therapeutic use; Antihypertensive Agents - therapeutic use; Arterial hypertension. Arterial hypotension; Asian Continental Ancestry Group - genetics; Biological and medical sciences; Blood and lymphatic vessels; Blood Pressure - drug effects; Blood Pressure - genetics; Cardiology. Vascular system; Case-Control Studies; Chi-Square Distribution; Clinical manifestations. Epidemiology. Investigative techniques. Etiology; Epithelial Sodium Channel Blockers - therapeutic use; Epithelial Sodium Channels - drug effects; Epithelial Sodium Channels - genetics; European Continental Ancestry Group - genetics; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Heterozygote; Humans; Hypertension - drug therapy; Hypertension - ethnology; Hypertension - genetics; Hypertension - physiopathology; Male; Medical sciences; Middle Aged; Namibia - epidemiology; Phenotype; Prevalence; South Africa - epidemiology; Treatment Outcome; Africa; South Africa; Namibia; blood pressure; ENaC; sodium channel; hypertension; R563Q; Africa; Hypertension; Sodium; Genotype; Cardiovascular disease; Arterial pressure; Blood pressure