Sex differences in brown adipose tissue activity and cold-induced thermogenesis

• Published in: Molecular and cellular endocrinology Vol. 534; p. 111365
• Main Authors: Herz, Carsten T., Kulterer, Oana C., Prager, Marlene, Marculescu, Rodrig, Langer, Felix B., Prager, Gerhard, Kautzky-Willer, Alexandra, Haug, Alexander R., Kiefer, Florian W.
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 20.08.2021
• Subjects: Adipose Tissue, Brown - diagnostic imaging; Adipose Tissue, Brown - metabolism; Adult; body fat; Brown adipose tissue; Calorimetry, Indirect; Cold Temperature; Cold-induced Thermogenesis; computed tomography; Estradiol; Estradiol - metabolism; Female; Fluorodeoxyglucose F18 - administration & dosage; heat production; Humans; Luteal Phase - metabolism; Male; Middle Aged; Positron Emission Tomography Computed Tomography - methods; positron-emission tomography; premenopause; Premenopause - metabolism; risk; Sex; Sex Characteristics; sexual dimorphism; Thermogenesis; Young Adult; CRP; WHR; Sex; Cold-induced Thermogenesis; TSH; UCP1; Brown adipose tissue; 18F-FDG; Estradiol; CIT; CT; HOMA-IR; BAT; SUV; RMR; FSH; LH; SHBG; PET; BMI

Brown adipose tissue (BAT) is suggested to exhibit a sexual dimorphism and thus contributes to the observed sex differences in cardiometabolic risk observed between women and men. Clinical data supporting this hypothesis are however scarce. The aim of this study was to investigate the relationship b...