Reaction of β-Nitrostyrene with Diethyl Malonate in the Presence of Bispidines: The Unusual Role of the Organocatalyst

• Published in: Chemistry an international journal Vol. 6; no. 3; pp. 387 - 406
• Main Authors: Dalinger, Alexander I., Mamedova, Sabina F., Burykina, Julia V., Pentsak, Evgeniy O., Vatsadze, Sergey Z.
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.06.2024
• Subjects: Aluminum; bispidines; Calibration; Catalysis; Chemical analysis; Chromatography; Infrared spectroscopy; Mass spectrometry; Michael addition; monoterpenoids; Nitrogen; nitroolefins; NMR spectroscopy; Software; Thermal analysis; Thermogravimetric analysis; Titration; β-nitrostyrene; United States > US; Germany

The aim of this work was the investigation of novel organocatalysts for the Michael addition of diethyl malonate to β-nitrostyrene. The methodology of the study included NMR titration, reaction monitoring by NMR spectroscopy and electrospray ionization mass spectrometry (ESI-MS), product characteriz...