Evidence for transforming Growth Factor-Beta 3 gene polymorphism in non-syndromic cleft lip and palate patients from Indian sub-continent

• Published in: Medicina oral, patología oral y cirugía bucal Vol. 17; no. 2; pp. e197 - e200
• Main Authors: Shaikh, S., Ravenndranath, R., Banerjee, M., Joseph, A., Jahgirdar, P.
• Format: Journal Article
• Language: English
• Published: Spain Medicina Oral S.L 01.03.2012
• Subjects: Cleft Lip - genetics; Cleft Palate - genetics; Humans; India; Oral Medicine and Pathology; Polymorphism, Genetic; Transforming Growth Factor beta3 - genetics; India

Orofacial clefts are major human birth defects with complex etiology. Previous studies have proposed Transforming growth factor - beta 3 (TGF-β3) gene as a key player in contributing to non-syndromic cleft lip and palate, however none of the studies have yet included Indian population. Hence this st...