In vitro evaluation on novel modified chitosan for targeted antitumor drug delivery - Qu, Ding; Lin, Haijiao; Zhang, Nan; Xue, Jingwei; Zhang, Can (Carbohydrate polymers, 2013)
Keywords: adenocarcinoma; Antineoplastic agents; Antineoplastic Agents - administration & dosage; Antineoplastic Agents - chemical synthesis; Antineoplastic Agents - chemistry; Applied sciences; Biological and medical sciences; Breast Neoplasms - drug therapy; carbon; Cellular uptake; Chemotherapy; Chitosan; Chitosan - administration & dosage; Chitosan - analogs & derivatives; Chitosan - chemical synthesis; Chitosan - chemistry; composite polymers; drug carriers; Drug Carriers - administration & dosage; Drug Carriers - chemical synthesis; Drug Carriers - chemistry; Exact sciences and technology; Female; folic acid; Folic Acid - administration & dosage; Folic Acid - chemical synthesis; Folic Acid - chemistry; Fourier transform infrared spectroscopy; Humans; in vitro studies; MCF-7 Cells; Medical sciences; Micelles; Natural polymers; nuclear magnetic resonance spectroscopy; Paclitaxel; Paclitaxel - administration & dosage; Paclitaxel - chemistry; Pharmacology. Drug treatments; Physicochemistry of polymers; Polymers - administration & dosage; Polymers - chemical synthesis; Polymers - chemistry; stable isotopes; Starch and polysaccharides; Tumor targeting; Cellular uptake; Chitosan; Tumor targeting; Micelles; Paclitaxel; Biological properties; Antineoplastic agent; Targeting; Cytotoxicity; Benzo[c]furan-1,3dione(1,3-dihydro); Drug carrier; Nanoencapsulation; Folic acid; Alkylation; Mechanism; Endocytosis; Micellar critical concentration; Tumor cell; Amphiphilic polymer; Control release polymer; Hydroxyalkylation; Experimental study; Chemical coupling; Chemical modification; Chitosan derivatives; Imidation; Internalization; Preparation; Oside polymer; Dialysis; Aqueous solution; Micellar solution