Functional brain network dysfunctions in subjects at high-risk for psychosis: A meta-analysis of resting-state functional connectivity

• Published in: Neuroscience and biobehavioral reviews Vol. 128; pp. 90 - 101
• Main Authors: Del Fabro, Lorenzo, Schmidt, André, Fortea, Lydia, Delvecchio, Giuseppe, D’Agostino, Armando, Radua, Joaquim, Borgwardt, Stefan, Brambilla, Paolo
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.09.2021
• Subjects: Clinical high risk; fMRI; Functional connectivity; Large-scale networks; Meta-analysis; Psychosis; Salience network; Functional connectivity; Psychosis; fMRI; Salience network; Clinical high risk; Large-scale networks; Meta-analysis

•Emerging evidence suggests altered functional connectivity in high-risk for psychosis.•This meta-analysis synthesizes results from 29 resting-state fMRI studies.•Clinical high-risk is associated with hypo-connectivity within the salience network.•Negative symptoms are correlated with functional con...