Immunostimulatory DNA sequences inhibit respiratory syncytial viral load, airway inflammation, and mucus secretion - Cho, Jae Youn; Miller, Marina; Baek, Kwang Je; Castaneda, Diego; Nayar, Jyothi; Roman, Mark; Raz, Eyal; Broide, David H. (Journal of allergy and clinical immunology, 2001)
Keywords: Adjuvants, Immunologic - therapeutic use; Allergic diseases; Animals; Asthma - drug therapy; Asthma - metabolism; Asthma - virology; Biological and medical sciences; Bronchial Hyperreactivity - diagnosis; Bronchitis - drug therapy; Bronchitis - virology; Bronchoconstrictor Agents; Cell Line; Chronic obstructive pulmonary disease, asthma; DNA - therapeutic use; Female; IFN-γ, asthma; Immunopathology; Immunostimulatory DNA sequence; Interferon-gamma - biosynthesis; Interferons - pharmacology; Interleukin-13 - biosynthesis; Lung - metabolism; Lung - virology; Medical sciences; methacholine; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucus - secretion; Pneumology; Respiratory and ent allergic diseases; Respiratory syncytial virus; Respiratory Syncytial Virus Infections - drug therapy; Respiratory Syncytial Virus Infections - metabolism; Respiratory Syncytial Virus Infections - virology; Respiratory Syncytial Viruses - growth & development; Respiratory Syncytial Viruses - isolation & purification; Viral Load; Virus Replication - drug effects; PAS; RSV; ISS; Penh; Immunostimulatory DNA sequence; M-ODN; respiratory syncytial virus; BAL; NK; IFN-γ, asthma; Animal model; Hyperreactivity; Spumavirinae; Prevention; Respiratory tract; Complication; Obstructive pulmonary disease; Mechanism of action; Aminoacid sequence; Immunostimulation; Respiratory disease; Rodentia; Retroviridae; Inflammation; Asthma; Infection; Virus; Vertebrata; Mammalia; Human syncytial virus; Mouse; Animal; DNA; Viral disease; Gamma interferon