Immunostimulatory DNA inhibits IL-4–dependent IgE synthesis by human B cells - Horner, Anthony A.; Widhopf, George F.; Burger, Jan A.; Takabayashi, Kenji; Cinman, Nadya; Ronaghy, Arash; Spiegelberg, Hans L.; Raz, Eyal (Journal of allergy and clinical immunology, 2001)
Keywords: allergy; Anti-Allergic Agents - pharmacology; B lymphocytes; B-Lymphocytes - drug effects; B-Lymphocytes - immunology; Biological and medical sciences; Cells, Cultured; CpG motif; DNA - immunology; DNA - pharmacology; Human; Humans; Hypersensitivity - immunology; Hypersensitivity, Immediate - immunology; IFN-γ receptor; IL-4 receptor; immuno-stimulatory DNA; Immunoglobulin A - biosynthesis; Immunoglobulin E - biosynthesis; Immunoglobulin G - biosynthesis; Immunoglobulin M - biosynthesis; Immunopathology; Immunotherapy (general aspects); Interleukin-4 - immunology; isotype switching; Medical sciences; Oligodeoxyribonucleotides - immunology; Oligodeoxyribonucleotides - pharmacology; Thionucleotides - immunology; Thionucleotides - pharmacology; vaccination; Human; B lymphocytes; ISS-ODN; MFIR; IL-4 receptor; immuno-stimulatory DNA; allergy; IFN-γR; M-ODN; IL-4R; IFN-γ receptor; isotype switching; vaccination; CpG motif; Immunopathology; Allergy; Immunoglobulins; Immunostimulation; Immune response; Nucleotide sequence; IgE; Cytokine; Isotype; Switching; Interleukin 4; Treatment; DNA; Immunotherapy; Gamma interferon; Biological receptor