Functional reorganization of the auditory pathways (or lack thereof) in callosal agenesis is predicted by monaural sound localization performance

• Published in: Neuropsychologia Vol. 48; no. 2; pp. 601 - 606
• Main Authors: Paiement, Philippe, Champoux, François, Bacon, Benoit A., Lassonde, Maryse, Mensour, Boualem, Leroux, Jean-Maxime, Lepore, Franco
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.01.2010; Elsevier
• Subjects: Acoustic Stimulation - methods; Adult; Adult and adolescent clinical studies; Agenesis of Corpus Callosum; Auditory Pathways - abnormalities; Auditory Pathways - blood supply; Auditory Pathways - pathology; Biological and medical sciences; Brain Mapping; Brain reorganization; Callosal agenesis; Case-Control Studies; Corpus Callosum - blood supply; Corpus Callosum - physiopathology; Female; fMRI; Functional Laterality - physiology; Humans; Image Processing, Computer-Assisted - methods; Magnetic Resonance Imaging - methods; Male; Medical sciences; Middle Aged; Organic mental disorders. Neuropsychology; Oxygen - blood; Plasticity; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Sound localization; Sound Localization - physiology; Temporal Lobe - pathology; Temporal Lobe - physiopathology; Brain reorganization; Sound localization; fMRI; Plasticity; Callosal agenesis; Human; Agenesis; Functional reorganization; Stimulus localization; tMRI; Monoaural hearing; Central nervous system; Space perception; Corpus callosum; Encephalon; Malformation; Auditory pathway; Predictive factor; Performance

Neuroimaging studies show that permanent peripheral lesions such as unilateral deafness cause functional reorganization in the auditory pathways. However, functional reorganization of the auditory pathways as a result of higher-level damage or abnormalities remains poorly investigated. A relatively...