Lowering Mutant Huntingtin Levels and Toxicity: Autophagy-Endolysosome Pathways in Huntington's Disease - Valionyte, Evelina; Yang, Yi; Roberts, Sheridan L.; Kelly, Jack; Lu, Boxun; Luo, Shouqing (Journal of molecular biology, 2020)
Keywords: Animals; Autophagy; Humans; Huntingtin; Huntingtin Protein - deficiency; Huntington Disease - metabolism; Huntington Disease - pathology; Huntington's disease; Lysosomes - metabolism; Lysosomes - pathology; mutants; Neurodegeneration; neurodegenerative diseases; Selective autophagy; toxicity; Huntingtin; ALS; HTT; mHTT; CK2; Autophagy; SNARE; TBK1; PI3K; Neurodegeneration; shRNA; UBA; mTOR; UPS; polyQ; ULK1/2; AD; Tollip; ASOs; TFEB; siRNA; Huntington's disease; ER; ATG; LIR; PE; STX-17; ROS; Selective autophagy; LAMP; HD; OPTN; PB1