Dose-Response Effect of Dietary Nitrate on Muscle Contractility and Blood Pressure in Older Subjects: A Pilot Study

• Published in: The journals of gerontology. Series A, Biological sciences and medical sciences Vol. 76; no. 4; p. 591
• Main Authors: Gallardo, Edgar J, Gray, Derrick A, Hoffman, Richard L, Yates, Brandon A, Moorthi, Ranjani N, Coggan, Andrew R
• Format: Journal Article
• Language: English
• Published: United States 01.04.2021
• Subjects: Isokinetic dynamometry; 3-Nitrotyrosine; Nitrite; Nitric oxide

We have recently demonstrated that dietary nitrate, a source of nitric oxide (NO) via the nitrate → nitrite → NO enterosalivary pathway, can improve muscle contractility in healthy older men and women. Nitrate ingestion has also been shown to reduce blood pressure in some, but not all, studies of ol...