Effect of bone morphogenetic proteins 2 and 4 on survival and development of bovine secondary follicles cultured in vitro

• Published in: Theriogenology Vol. 110; pp. 44 - 51
• Main Authors: da Cunha, E.V., Melo, L.R.F., Sousa, G.B., Araújo, V.R., Vasconcelos, G.L., Silva, A.W.B., Silva, J.R.V.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2018
• Subjects: Antrum; Cattle; Expression; Ovary; Preantral; Viability; Ovary; Preantral; Antrum; Cattle; Expression; Viability

This study evaluated the effect of bone morphogenetic proteins 2 (BMP2) and 4 (BMP2) on follicle development and mRNA expression for GDF9, Cyclin B1, BMPR1A, BMPR1B, BMPRII, FSHR and SMAD1 in bovine secondary follicles cultured in vitro. Isolated secondary follicles were cultured for 18 days in TCM1...