The Spectrum of Germline Nucleotide Variants in Gastric Cancer Patients in the Kyrgyz Republic

• Published in: Current Issues in Molecular Biology Vol. 45; no. 8; pp. 6383 - 6394
• Main Authors: Bilyalov, Airat, Nikolaev, Sergey, Danishevich, Anastasiia, Khatkov, Igor, Makhmudov, Komron, Isakova, Zhainagul, Bakirov, Nurbek, Omurbaev, Ernis, Osipova, Alena, Ramaldanov, Ramaldan, Shagimardanova, Elena, Kiyasov, Andrey, Gusev, Oleg, Bodunova, Natalia
• Format: Journal Article
• Language: English
• Published: MDPI AG 31.07.2023; MDPI
• Subjects: Analysis; Cancer; Cancer patients; Care and treatment; Communication; Ethylenediaminetetraacetic acid; gastric cancer; Gene mutations; Genetic aspects; Health aspects; hereditary cancer; NGS; Oncology, Experimental; Stomach cancer; Surveys; Tumor proteins; Kyrgyzstan

Gastric cancer is a major challenge in modern oncology due to its high detection rate and prevalence. While sporadic cases make up the majority of gastric cancer, hereditary gastric cancer is caused by germline mutations in several genes linked to different syndromes. Thus, identifying hereditary fo...