Rosmarinus officinalis essential oil: A review of its phytochemistry, anti-inflammatory activity, and mechanisms of action involved

• Published in: Journal of ethnopharmacology Vol. 229; pp. 29 - 45
• Main Authors: Borges, Raphaelle Sousa, Ortiz, Brenda Lorena Sánchez, Pereira, Arlindo César Matias, Keita, Hady, Carvalho, José Carlos Tavares
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 30.01.2019
• Subjects: 8-cineole; alpha-pinene; Animals; anti-inflammatory activity; Anti-Inflammatory Agents - chemistry; Anti-Inflammatory Agents - pharmacology; Anti-Inflammatory Agents - therapeutic use; Antioxidant; antioxidant activity; arachidonic acid; bioavailability; Camphor; cineole; clinical trials; essential oils; Humans; Inflammation; mechanism of action; Monoterpenes; muscle relaxants; nanoemulsions; oils; Oils, Volatile - chemistry; Oils, Volatile - pharmacology; Oils, Volatile - therapeutic use; Phytochemicals - analysis; Phytotherapy; Rosmarinus; Rosmarinus officinalis; Salvia; signal transduction; smooth muscle; toxicity; traditional medicine; transcription factor NF-kappa B; α-pinene; HMGB; TREM; DMSO; LT; α-pinene; MPO; NF-κB; iNOS; Monoterpenes; MAPKs; AA; IL; DPPH; MIC; MMP; VCAM; 1; NOS; LOX; TST; MIP; ROS; Ig; NO; fMLP; TPA; EORO; NLRP-3; LPS; IFN; 8-cineole; TLR; ABST; ICAM; ISO; Inflammation; TNBS; Antioxidant; COX; p.o; PAMP; STAT; TNF-α; JAK; MKP-1; Camphor; PG; MCP; DAMP

Plant species Rosmarinus officinalis L. (Lamiaceae; Synonyms: Salvia rosmarinus Schleid. and Rosmarinus angustifolius Mill.) is a herb widely used worldwide. In local and traditional medicine, its used for inflammation-related diseases. Currently, studies report anti-inflammatory activity in its ess...