Survival and Proliferation under Severely Hypoxic Microenvironments Using Cell-Laden Oxygenating Hydrogels

• Published in: Journal of functional biomaterials Vol. 12; no. 2; p. 30
• Main Authors: Hassan, Shabir, Cecen, Berivan, Peña-Garcia, Ramon, Marciano, Fernanda Roberta, Miri, Amir K., Fattahi, Ali, Karavasili, Christina, Sebastian, Shikha, Zaidi, Hamza, Lobo, Anderson Oliveira
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 02.05.2021; MDPI
• Subjects: Aluminum; Anoxia; Artificial tissues; Biomaterials; Biomedical materials; Calcium; Cell culture; Cell survival; cells; electrospray; Encapsulation; Gelatin; Hydrogels; Hydrolysis; Hypoxia; Intermediates; Ischemia; Lasers; Metabolism; Microenvironments; Microparticles; Morphology; Myoblasts; Necrosis; Nutrients; Oxygen; Peroxide; Polycaprolactone; Polyethylene glycol; Reactive oxygen species; Respiration; sever hypoxia; Surgical implants; Survival; Vascularization; St Louis Missouri; United States > US

Different strategies have been employed to provide adequate nutrients for engineered living tissues. These have mainly revolved around providing oxygen to alleviate the effects of chronic hypoxia or anoxia that result in necrosis or weak neovascularization, leading to failure of artificial tissue im...