Effects of early-life stress on probabilistic reversal learning and response perseverance in young adults

• Published in: Neurobiology of learning and memory Vol. 205; p. 107839
• Main Authors: Franco, Corinna Y., Knowlton, Barbara J.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2023
• Subjects: Adverse Childhood Experiences; Child; Early-life stress; Habit; Habits; Human; Humans; Learning; Reinforcement, Psychology; Reversal Learning; Stress, Psychological; Substance-Related Disorders; Young Adult; Habit; Learning; Early-life stress; Human; Reversal learning
• ISSN: 1074-7427; 1095-9564; 1095-9564
• DOI: 10.1016/j.nlm.2023.107839

•Individuals who report experiencing early-life stress demonstrate greater perseveration after contingency reversal.•Sexual abuse and emotional neglect during childhood showed the most robust association with reduced cognitive flexibility.•Perseveration after reversal in the probabilistic classifica...