Probable delirium is a presenting symptom of COVID-19 in frail, older adults: a cohort study of 322 hospitalised and 535 community-based older adults

• Published in: Age and ageing Vol. 50; no. 1; pp. 40 - 48
• Main Authors: Zazzara, Maria Beatrice, Penfold, Rose S, Roberts, Amy L, Lee, Karla A, Dooley, Hannah, Sudre, Carole H, Welch, Carly, Bowyer, Ruth C E, Visconti, Alessia, Mangino, Massimo, Freidin, Maxim B, El-Sayed Moustafa, Julia S, Small, Kerrin S, Murray, Benjamin, Modat, Marc, Graham, Mark S, Wolf, Jonathan, Ourselin, Sebastien, Martin, Finbarr C, Steves, Claire J, Lochlainn, Mary Ni
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 08.01.2021; Oxford Publishing Limited (England)
• Subjects: Aged; Cohort analysis; Cohort Studies; Community; Comorbidity; Coronaviruses; Cough; Cough reflex; COVID-19; COVID-19 - epidemiology; COVID-19 - psychology; COVID-19 - therapy; COVID-19 Nucleic Acid Testing - methods; COVID-19 Nucleic Acid Testing - statistics & numerical data; Delirium; Delirium - diagnosis; Delirium - epidemiology; Delirium - etiology; Fatigue; Female; Fever; Frail; Frail Elderly; Frailty; Frailty - diagnosis; Frailty - epidemiology; Frailty - etiology; Geriatric Assessment - methods; Hospitalization; Hospitalization - statistics & numerical data; Humans; London - epidemiology; Male; Medical screening; Older people; Polymerase chain reaction; Prevalence; Regression analysis; Research Paper; Risk Assessment - methods; Risk Factors; SARS-CoV-2 - isolation & purification; Self report; Symptoms; Vulnerability; London; COVID-19; frailty; older people; delirium

Abstract Background Frailty, increased vulnerability to physiological stressors, is associated with adverse outcomes. COVID-19 exhibits a more severe disease course in older, comorbid adults. Awareness of atypical presentations is critical to facilitate early identification. Objective To assess how...