Changes in serum thyroxine and thyroid-stimulating hormone concentrations in epileptic dogs receiving phenobarbital for one year

• Published in: Journal of veterinary pharmacology and therapeutics Vol. 23; no. 4; pp. 243 - 249
• Main Authors: GASKILL, C.L., BURTON, S.A., GELENS, H.C.J., IHLE, S.L., MILLER, J.B., SHAW, D.H., BRIMACOMBE, M.B., CRIBB, A.E.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 04.08.2000
• Subjects: Analysis of Variance; Animals; Anticonvulsants - pharmacology; Anticonvulsants - therapeutic use; Dog Diseases - drug therapy; Dogs; Epilepsy - drug therapy; Epilepsy - veterinary; Female; Male; Phenobarbital - pharmacology; Phenobarbital - therapeutic use; Prospective Studies; Thyrotropin - blood; Thyrotropin - drug effects; Thyroxine - blood; Thyroxine - drug effects

A multicentric prospective study was conducted to monitor the effect of phenobarbital on serum total thyroxine (T4) and thyroid‐stimulating hormone (TSH) concentrations in epileptic dogs. Serum T4 concentrations were determined for 22 epileptic dogs prior to initiation of phenobarbital therapy (time...