EO9 (Apaziquone): from the clinic to the laboratory and back again - Phillips, Roger M; Hendriks, Hans R; Peters, Godefridus J (British journal of pharmacology, 2013)
Keywords: Administration, Intravesical; Animals; Antineoplastic Agents - pharmacokinetics; Antineoplastic Agents - pharmacology; Antineoplastic Agents - therapeutic use; Apaziquone; Area Under Curve; Aziridines - pharmacology; bioreductive prodrugs; bladder cancer; Carcinoma, Non-Small-Cell Lung - drug therapy; Carcinoma, Transitional Cell - drug therapy; Carcinoma, Transitional Cell - pathology; Clinical trials; Disease Models, Animal; Drug Delivery Systems; EO9; Eoquin; Humans; hypoxia; Immunohistochemistry; Indolequinones - pharmacology; Lung Neoplasms - drug therapy; NQO1; Pharmaceutical industry; Reviews; Treatment Failure; Urinary Bladder - drug effects; Urinary Bladder - pathology; Urinary Bladder Neoplasms - drug therapy; Urinary Bladder Neoplasms - pathology