Efficacy and safety of the SQ‐standardized grass allergy immunotherapy tablet in mono‐ and polysensitized subjects

• Published in: Allergy (Copenhagen) Vol. 68; no. 2; pp. 252 - 255
• Main Authors: Nelson, H., Blaiss, M., Nolte, H., Würtz, S. Ø., Andersen, J. S., Durham, S. R.
• Format: Journal Article
• Language: English
• Published: Denmark Blackwell Publishing Ltd 01.02.2013
• Subjects: Administration, Sublingual; Adult; Allergies; Antigens, Plant - immunology; Child; Child, Preschool; Data processing; Desensitization, Immunologic - methods; Double-Blind Method; Female; Follow-Up Studies; grass allergy; Grasses; Humans; Hypersensitivity; Immunotherapy; Male; Patient Safety; Phleum pratense; Phytotherapy - methods; Plant Extracts - therapeutic use; Poaceae - immunology; polysensitization; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Seasonal - drug therapy; Rhinitis, Allergic, Seasonal - immunology; Rhinitis, Allergic, Seasonal - physiopathology; rhinoconjunctivitis; Risk Assessment; Severity of Illness Index; Statistical analysis; sublingual immunotherapy; Tablets; Tablets - administration & dosage; Treatment Outcome

The efficacy of single‐allergen‐specific immunotherapy in polysensitized subjects is a matter of debate. We therefore performed a post hoc analysis of pooled data from six randomized, double‐blind, placebo‐controlled trials (N = 1871) comparing the efficacy and safety of the SQ‐standardized grass al...