ICAM‐1 expression and the soluble ICAM‐1 level for evaluating the metastatic potential of gastric cancer

• Published in: International journal of cancer Vol. 100; no. 4; pp. 486 - 490
• Main Authors: Maruo, Yukinobu, Gochi, Akira, Kaihara, Akihiko, Shimamura, Hiroshi, Yamada, Takatoshi, Tanaka, Noriaki, Orita, Kunzo
• Format: Journal Article
• Language: English
• Published: New York Wiley Subscription Services, Inc., A Wiley Company 01.08.2002; Wiley-Liss
• Subjects: Biological and medical sciences; Biomarkers, Tumor - blood; Biomarkers, Tumor - metabolism; gastric cancer; Gastroenterology. Liver. Pancreas. Abdomen; hematogenous metastasis; Humans; ICAM‐1; Immunohistochemistry; Intercellular Adhesion Molecule-1 - biosynthesis; Intercellular Adhesion Molecule-1 - blood; Intercellular Adhesion Molecule-1 - metabolism; Medical sciences; Neoplasm Metastasis; Prognosis; Solubility; Stomach Neoplasms - blood; Stomach Neoplasms - diagnosis; Stomach Neoplasms - metabolism; Stomach Neoplasms - pathology; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; s‐ICAM‐1; tumor invasion; Tumors; Human; Stomach; Immunoglobulins; Intercellular adhesion molecule 1; Cell adhesion molecule; Digestive diseases; Soluble form; Metastasis; Malignant tumor; Blood dissemination; Gastric disease
• ISSN: 0020-7136; 1097-0215
• DOI: 10.1002/ijc.10514

ICAM‐1 plays an important role in cell–cell and cell–extracellular matrix interactions, especially tumor invasion and cytotoxicity of lymphocytes. In the present study, the relationship between metastasis of gastric cancer and ICAM‐1 expression by cancer cells or the serum level of s‐ICAM‐1 was (s‐I...