Identification of Pseudomonas aeruginosa genes required for epithelial cell injury

We have developed a simple, reproducible and rapid genetic screen for Pseudomonas aeruginosa‐induced epithelial cell cytotoxicity in cultures of MDCK cells. This screen was used to isolate isogenic transposon‐tagged non‐cytotoxic mutants of a cytotoxic and lung‐virulent strain of P. aeruginosa (PA10...

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Published inMolecular microbiology Vol. 24; no. 6; pp. 1249 - 1262
Main Authors Jung Kang, Pil, Hauser, Alan R., Apodaca, Gerard, Fleiszig, Suzanne M. J., Wiener‐Kronish, Jeanine, Mostov, Keith, Engel, Joanne N.
Format Journal Article
LanguageEnglish
Published Oxford UK Blackwell Science Ltd 01.06.1997
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