Epigenetic and immunological indicators of IPEX disease in subjects with FOXP3 gene mutation - Narula, Mansi; Lakshmanan, Uma; Borna, Simon; Schulze, Janika J.; Holmes, Tyson H.; Harre, Nicholas; Kirkey, Matthew; Ramachandran, Akshaya; Tagi, Veronica Maria; Barzaghi, Federica; Grunebaum, Eyal; Upton, Julia E.M.; et al. (Journal of allergy and clinical immunology, 2023)
Keywords: atypical IPEX; CD4+ Teff; CyTOF; cytokines; Epigenesis, Genetic; epigenetic; Forkhead Transcription Factors; FOXP3; Genetic Diseases, X-Linked; Humans; Mutation; Polyendocrinopathies, Autoimmune; T-Lymphocytes, Regulatory; TH2; Treg cells; TSDR demethylation; typical IPEX; typical IPEX; epigenetic; T1D; Treg; IS; TSDR; FOXP3; CD4+ Teff; MFI; TSDR demethylation; Teff; IPEX; Treg cells; atypical IPEX; cytokines; HD; CyTOF; autoAb; T1D-GRS; TH2; CD4(+) Teff; T(H)2