Microdot Accumulation in the Anterior Cornea with Aging - Quantitative Analysis with in Vivo Confocal Microscopy

• Published in: Current eye research Vol. 45; no. 9; pp. 1058 - 1064
• Main Authors: Utheim, Tor Paaske, Chen, Xiangjun, Fricke, Otto, Bergersen, Linda Hildegard, Lagali, Neil
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 01.09.2020
• Subjects: aging; corneal degeneration; corneal stroma; in vivo confocal microscopy; lipofuscin; Microdot deposits; Microdot deposits; in vivo confocal microscopy; lipofuscin; corneal degeneration; corneal stroma; aging

Degenerative 'microdot' deposits in healthy and hypoxic corneas are believed to represent lipofuscin-like material aggregation in the stroma. To accurately assess microdot deposits in a clinical setting, we sought to quantify these deposits for the first time using the non-invasive clinica...