Comparison of treatment effect between phase 2 and phase 3 trials in patients with inflammatory bowel disease

• Published in: United European gastroenterology journal Vol. 11; no. 8; pp. 797 - 806
• Main Authors: Wils, Pauline, Jairath, Vipul, Sands, Bruce E., Magro, Fernando, Reinisch, Walter, Rubin, David, Danese, Silvio, Baumann, Cédric, Peyrin‐Biroulet, Laurent
• Format: Journal Article
• Language: English
• Published: Nijmegen John Wiley & Sons, Inc 01.10.2023; John Wiley and Sons Inc
• Subjects: Biological products; Clinical trials; Costs; Crohns disease; Drug development; Drug dosages; Endoscopy; Inflammatory Bowel Disease; Original; Patients; Quality of life; Remission (Medicine); Success

Abstract Background and Aims The accumulation of multiple randomized controlled trials in the field of inflammatory bowel diseases provides an opportunity to compare treatment effects between phase 2 and 3 trials. We aimed to determine whether treatment effects observed in phase 3 investigating biol...