Less Is More: Structures of Difficult Targets with Minimal Constraints

• Published in: Structure (London) Vol. 22; no. 9; pp. 1223 - 1224
• Main Authors: Lloyd, Neil R., Wuttke, Deborah S.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 02.09.2014
• Subjects: Carrier Proteins - chemistry; Glycoproteins - chemistry; Viral Proteins - chemistry

By merging recent experimental and computational methodology advances, resolution-adapted structural recombination Rosetta has emerged as a powerful strategy for solving the structure of traditionally challenging targets. In this issue of Structure, Sgourakis and colleagues solve the structure of on...