ZEA mediates autophagy through the ROS-AMPK-m-TOR pathway to enhance the susceptibility of mastitis induced by Staphylococcus aureus in mice

• Published in: Ecotoxicology and environmental safety Vol. 266; p. 115548
• Main Authors: He, Yuhong, Su, Niri, Yang, Hengyi, Yang, Wencheng, Zhao, Caijun, Fu, Yunhe, Hu, Yubo, Hu, Xiaoyu
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.11.2023; Elsevier
• Subjects: AMPK-mTOR; Autophagy; ROS; S. aureus; Zearalenone; NAC; S. aureus; AMPK-mTOR; ROS; mTOR; AMPK; Zearalenone; MMEC; LC3; Autophagy; CQ

Mastitis is an inflammatory response of the mammary tissue caused by pathogenic bacterial infections, especially Staphylococcus aureus (S. aureus). Zearalenone (ZEA) is one of the common mycotoxins in moldy feed, which usually affects the cow's resistance to pathogenic microorganisms. However,...