Constrained peptides as binding entities
Displaying proteins and peptides on genetic packages and selecting packages that display high-affinity binders allows large numbers of peptidyl compounds to be tested for binding to targets. Phage-displayed libraries of unstructured peptides (UPs) have yielded binders for some targets, but not for m...
Saved in:
| Published in | Trends in biotechnology (Regular ed.) Vol. 13; no. 10; pp. 426 - 430 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
Oxford
Elsevier Ltd
01.10.1995
Elsevier Science |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Displaying proteins and peptides on genetic packages and selecting packages that display high-affinity binders allows large numbers of peptidyl compounds to be tested for binding to targets. Phage-displayed libraries of unstructured peptides (UPs) have yielded binders for some targets, but not for many others. Therefore, more attention is being paid to peptidyl compounds that have varied regions that are subject to conformational constraint. |
|---|---|
| AbstractList | Displaying proteins and peptides on genetic packages and selecting packages that display high-affinity binders allows large numbers of peptidyl compounds to be tested for binding to targets. Phage-displayed libraries of unstructured peptides (UPs) have yielded binders for some targets, but not for many others. Therefore, more attention is being paid to peptidyl compounds that have varied regions that are subject to conformational constraint. Displaying proteins and peptides on genetic packages and selecting packages that display high-affinity binders allows large numbers of peptidyl compounds to be tested for binding to targets. Phage-displayed libraries of unstructured peptides (UPs) have yielded binders for some targets, but not for many others. Therefore, more attention is being paid to peptidyl compounds that have varied regions that are subject to conformational constraint.Displaying proteins and peptides on genetic packages and selecting packages that display high-affinity binders allows large numbers of peptidyl compounds to be tested for binding to targets. Phage-displayed libraries of unstructured peptides (UPs) have yielded binders for some targets, but not for many others. Therefore, more attention is being paid to peptidyl compounds that have varied regions that are subject to conformational constraint. |
| Author | Ladner, Robert C. |
| Author_xml | – sequence: 1 givenname: Robert C. surname: Ladner fullname: Ladner, Robert C. organization: Protein Engineering Corporation, 765 Concord Avenue, Cambridge, MA 02138, USA |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3669041$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/7546567$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkctKAzEUhoMo2qqPIHQhoovRk8ltgguR4g0KLtR1SDNnJDLN1CQVfHunF7pw003O4nz_DznfkOyHLiAhZxSuKVB589Y_qlBK60uAq6rSWhWwRwa0UrpgoOU-GWyRIzJM6QsAmNL0kBwqwaWQakAux11IOVofsB7NcZ59jWlk02jqQ-3D5whD9tljOiEHjW0Tnm7mMfl4fHgfPxeT16eX8f2kcFzQXLgGJROCSlTIeWOBCbSs0ZyJZurAWlmWsqxqLVhloQReSuwxYSkrucOaHZOLde88dt8LTNnMfHLYtjZgt0hGKaGEFrATpLqqJAe-GxR9o1RVD55twMV0hrWZRz-z8ddsjtXvzzd7m5xtm2iD82mLMSk1cNpjYo252KUUsdkSFMxSnVmpM0svBsCs1Jnlh27_5ZzPNvsuLP20O9N36zT2cn48RpOcx9Cf1Ed02dSd39HwB8_tsGo |
| CODEN | TRBIDM |
| CitedBy_id | crossref_primary_10_1007_s00018_009_0031_5 crossref_primary_10_1021_ja400461h crossref_primary_10_1021_ci100431r crossref_primary_10_1016_j_jmb_2005_08_001 crossref_primary_10_1158_1541_7786_170_2_3 crossref_primary_10_1016_S0959_440X_97_80108_X crossref_primary_10_1517_14712598_5_6_783 crossref_primary_10_1007_s12033_019_00156_8 crossref_primary_10_1021_ac701688q crossref_primary_10_1021_acs_accounts_7b00184 crossref_primary_10_1515_HMBCI_2011_013 crossref_primary_10_1021_cr960065d crossref_primary_10_1002_jmr_523 crossref_primary_10_1038_s41417_019_0156_0 crossref_primary_10_1016_S0734_9750_00_00054_9 crossref_primary_10_1093_nar_26_2_623 crossref_primary_10_1002__SICI_1099_1352_199709_10_10_5_217__AID_JMR371_3_0_CO_2 crossref_primary_10_1073_pnas_110538897 crossref_primary_10_1038_sj_gt_3302009 crossref_primary_10_1016_j_cbpa_2011_03_009 crossref_primary_10_1517_17460441_1_5_491 crossref_primary_10_1002_jcc_27130 crossref_primary_10_1021_bp010181o crossref_primary_10_1002__SICI_1097_0282_200002_53_2_200__AID_BIP10_3_0_CO_2_L crossref_primary_10_1371_journal_pone_0193332 crossref_primary_10_1016_j_jim_2006_08_009 crossref_primary_10_1002_cbdv_200690087 crossref_primary_10_3390_molecules16053499 crossref_primary_10_1021_acs_orglett_4c00602 crossref_primary_10_1038_nchembio_259 crossref_primary_10_1007_BF01908535 crossref_primary_10_1155_2012_295719 crossref_primary_10_1016_S0141_0229_03_00118_2 crossref_primary_10_1016_S1773_035X_09_70313_2 crossref_primary_10_3390_ijms14046690 crossref_primary_10_1038_sj_bjc_6602143 crossref_primary_10_1016_j_jmb_2007_05_052 crossref_primary_10_1081_RRS_120014608 crossref_primary_10_1139_w98_015 crossref_primary_10_1146_annurev_biophys_26_1_401 crossref_primary_10_1371_journal_pone_0103397 crossref_primary_10_1073_pnas_95_6_2902 crossref_primary_10_4155_fmc_10_259 crossref_primary_10_1016_j_bbrc_2006_02_126 crossref_primary_10_1002_bit_20644 crossref_primary_10_1002_bit_20124 crossref_primary_10_1002_anie_200461786 crossref_primary_10_1016_j_bmc_2010_06_053 crossref_primary_10_1007_s00216_019_01862_7 crossref_primary_10_18632_oncotarget_297 crossref_primary_10_1016_S0968_0896_02_00166_9 crossref_primary_10_1002_anie_201006630 crossref_primary_10_1039_D4SC01992J crossref_primary_10_1021_jm9604078 crossref_primary_10_1016_S0378_4347_98_00052_8 crossref_primary_10_1006_jmbi_2000_3850 crossref_primary_10_1016_j_bios_2011_06_012 crossref_primary_10_1016_S1359_6446_98_01220_3 crossref_primary_10_1016_S0958_1669_97_80065_1 crossref_primary_10_3390_molecules16021625 crossref_primary_10_1093_protein_gzq012 crossref_primary_10_3390_e11010062 crossref_primary_10_1016_j_chembiol_2004_03_004 crossref_primary_10_1038_sj_cr_7290190 crossref_primary_10_1263_jbb_99_448 crossref_primary_10_1016_j_jconrel_2024_10_014 crossref_primary_10_1038_sj_onc_1204805 crossref_primary_10_1007_BF03182687 crossref_primary_10_1002_psc_717 crossref_primary_10_1074_jbc_275_8_5648 crossref_primary_10_1111_j_1399_3011_2005_00258_x crossref_primary_10_1002_ange_201006630 crossref_primary_10_1039_C5BM00004A crossref_primary_10_1016_S1389_0352_01_00019_8 crossref_primary_10_1016_S0009_9120_02_00343_0 crossref_primary_10_1074_jbc_M610722200 crossref_primary_10_1016_S0960_0760_01_00085_1 crossref_primary_10_1002__SICI_1097_0134_19990801_36_2_217__AID_PROT7_3_0_CO_2_X crossref_primary_10_1093_protein_gzr019 crossref_primary_10_1002_ange_200461786 crossref_primary_10_1016_j_envint_2004_09_002 crossref_primary_10_1002_psc_392 |
| Cites_doi | 10.1021/bi00108a016 10.1016/0378-1119(88)90495-7 10.4049/jimmunol.154.7.3162 10.1021/bi00495a002 10.1016/S0021-9258(17)31765-9 10.1016/S0021-9258(17)31766-0 10.1002/j.1460-2075.1994.tb06501.x 10.1083/jcb.124.3.373 10.1038/nbt0395-265 10.1126/science.1696028 10.1126/science.7529940 10.1016/0167-7799(94)90079-5 10.1016/0952-7915(93)90016-L 10.1016/0378-1119(93)90155-V 10.1006/jmbi.1993.1623 10.1002/j.1460-2075.1994.tb06540.x 10.1016/0378-1119(93)90149-W 10.4049/jimmunol.153.2.724 10.1016/0378-1119(93)90150-2 10.1021/bi00116a037 10.1126/science.2143033 10.1016/0378-1119(93)90153-T 10.1126/science.7526465 |
| ContentType | Journal Article |
| Copyright | 1995 Elsevier Science Ltd 1995 INIST-CNRS |
| Copyright_xml | – notice: 1995 Elsevier Science Ltd – notice: 1995 INIST-CNRS |
| DBID | AAYXX CITATION IQODW CGR CUY CVF ECM EIF NPM 7QO 8FD FR3 P64 7X8 |
| DOI | 10.1016/S0167-7799(00)88997-0 |
| DatabaseName | CrossRef Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Biotechnology Research Abstracts Technology Research Database Engineering Research Database Biotechnology and BioEngineering Abstracts MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Engineering Research Database Biotechnology Research Abstracts Technology Research Database Biotechnology and BioEngineering Abstracts MEDLINE - Academic |
| DatabaseTitleList | MEDLINE Engineering Research Database MEDLINE - Academic Engineering Research Database |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Engineering Chemistry |
| EISSN | 1879-3096 |
| EndPage | 430 |
| ExternalDocumentID | 301684133 7546567 3669041 10_1016_S0167_7799_00_88997_0 S0167779900889970 |
| Genre | Journal Article Review |
| GroupedDBID | --- --K --M -~X .1- .DC .FO .~1 0R~ 123 1B1 1P~ 1RT 1~. 1~5 29Q 3V. 4.4 457 4G. 53G 5VS 7-5 71M 7X7 88E 8AO 8FE 8FG 8FH 8FI 8FJ 8G5 8P~ 9JM 9JN AABNK AACTN AAEDT AAEDW AAIAV AAIKC AAIKJ AAKOC AALRI AAMNW AAOAW AAQFI AAQXK AAXUO ABFNM ABFRF ABGSF ABJCF ABJNI ABLJU ABMAC ABNUV ABUDA ABUWG ABXDB ABYKQ ACDAQ ACGFO ACGFS ACIWK ACPRK ACRLP ADBBV ADEWK ADEZE ADFRT ADMUD ADUVX AEBSH AEFWE AEHWI AEKER AENEX AEVXI AFCTW AFKRA AFKWA AFRAH AFRHN AFTJW AFXIZ AGHFR AGRDE AGUBO AGYEJ AHHHB AHMBA AHPOS AIEXJ AIKHN AITUG AJBFU AJOXV AJUYK AKURH ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ AQUVI ARAPS ASPBG AVWKF AXJTR AZFZN AZQEC BBNVY BENPR BGLVJ BHPHI BKOJK BLXMC BPHCQ BVXVI CCPQU CS3 DOVZS DU5 DWQXO EBS EFJIC EFLBG EJD ENUVR EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN FYUFA G-2 G-Q G8K GBLVA GNUQQ GUQSH HCIFZ HLW HMCUK HVGLF HZ~ IHE J1W KOM L6V LK8 LX3 M0T M1P M2O M41 M7P M7S MO0 MVM N9A O-L O9- O9. OAUVE OK~ OZT P-8 P-9 P2P P62 PC. PQQKQ PROAC PSQYO PTHSS Q38 R2- RCE RIG RNS ROL RPZ SBG SCC SDF SDG SDP SES SEW SPC SPCBC SSG SSU SSZ T5K TAE TN5 UKHRP WUQ XFK XPP Y6R Z5R ZGI ZMT ~02 ~G- ~KM AAHBH AAMRU AATTM AAXKI AAYWO AAYXX ABDPE ABWVN ACRPL ACVFH ADCNI ADNMO AEIPS AEUPX AEUYN AFPUW AGCQF AGQPQ AGRNS AIGII AIIUN AKBMS AKRWK AKYEP ALIPV ANKPU APXCP BNPGV CITATION PHGZM PHGZT SSH IQODW CGR CUY CVF ECM EIF NPM 7QO 8FD FR3 P64 7X8 |
| ID | FETCH-LOGICAL-c451t-cfe635516e7e44fa035ea3f9435fbc0aa622628d9538a020426e4fa5a1324ced3 |
| IEDL.DBID | AIKHN |
| ISSN | 0167-7799 |
| IngestDate | Thu Jul 10 17:38:38 EDT 2025 Fri Jul 11 15:36:26 EDT 2025 Fri Jul 11 09:27:23 EDT 2025 Wed Feb 19 01:10:34 EST 2025 Wed Apr 02 07:18:09 EDT 2025 Thu Apr 24 23:08:03 EDT 2025 Tue Jul 01 01:12:02 EDT 2025 Fri Feb 23 02:32:23 EST 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 10 |
| Keywords | Ligand binding Affinity Specificity Review Peptides |
| Language | English |
| License | https://www.elsevier.com/tdm/userlicense/1.0 CC BY 4.0 |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c451t-cfe635516e7e44fa035ea3f9435fbc0aa622628d9538a020426e4fa5a1324ced3 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 ObjectType-Review-3 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
| PMID | 7546567 |
| PQID | 15575678 |
| PQPubID | 23462 |
| PageCount | 5 |
| ParticipantIDs | proquest_miscellaneous_77575950 proquest_miscellaneous_19886404 proquest_miscellaneous_15575678 pubmed_primary_7546567 pascalfrancis_primary_3669041 crossref_primary_10_1016_S0167_7799_00_88997_0 crossref_citationtrail_10_1016_S0167_7799_00_88997_0 elsevier_sciencedirect_doi_10_1016_S0167_7799_00_88997_0 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 1900 |
| PublicationDate | 1995-10-01 |
| PublicationDateYYYYMMDD | 1995-10-01 |
| PublicationDate_xml | – month: 10 year: 1995 text: 1995-10-01 day: 01 |
| PublicationDecade | 1990 |
| PublicationPlace | Oxford |
| PublicationPlace_xml | – name: Oxford – name: England |
| PublicationTitle | Trends in biotechnology (Regular ed.) |
| PublicationTitleAlternate | Trends Biotechnol |
| PublicationYear | 1995 |
| Publisher | Elsevier Ltd Elsevier Science |
| Publisher_xml | – name: Elsevier Ltd – name: Elsevier Science |
| References | Koivunen, Wang, Ruoslahti (bib20) 1995; 13 Devlin, Panganiban, Devlin (bib26) 1990; 249 5223409 Dennis, Lazarus (bib22) 1994; 269 WO90/02809 Brendt, Guntert, Wuthrich (bib9) 1993; 234 Hynes, Randal, Kennedy, Eigenbrot, Kossiakoff (bib10) 1990; 29 Leatherbarrow, Salcinski (bib18) 1991; 30 Folgori (bib30) 1994; 13 Clackson, Wells (bib4) 1994; 12 Kay, Adey, He, Manfredi, Mataragnon, Fowlkes (bib27) 1993; 128 Dennis, Lazarus (bib21) 1994; 269 Hoess, Mack, Walton, Reilly (bib17) 1994; 153 Creighton, Charles (bib8) 1987; 52 Roberts (bib28) 1992; 89 Balass, Heldman, Cabilly, Givol, Katchalski-Katzir, Fuchs (bib12) 1993; 90 Clackson, Wells (bib23) 1995; 267 Ladner, R. C., Guterman, S. K., Roberts, R. L., Markland, W., Ley, A. C. and Kent, R. B. (1993) Meola (bib31) 1995; 154 Cwirla, Peters, Barrett, Dower (bib14) 1990; 87 Ladner, R. C. and Guterman, S. K. (1990) Parmley, Smith (bib1) 1988; 73 Ladner, R. C., in McLafferty, Kent, Ladner, Markland (bib16) 1993; 128 Pinilla, Appel, Houghten (bib15) 1993; 128 (Kay, B.,Winter, J. McCafferty, J., eds) Academic Press (in press). Koivunen, Wang, Ruoslahti (bib19) 1994; 124 Feng, Chen, Yu, Simon, Schreiber (bib24) 1994; 266 de (bib11) 1992; 31 Scott, Smith (bib25) 1990; 249 Smith, Schultz, Ladbury (bib29) 1993; 128 Lane, Stephan (bib5) 1993; 5 Cunningham, Lowe, Li, Bennett, Wells (bib6) 1994; 13 Goodson, Doyle, Kaufman, Rosenberg (bib13) 1994; 91 Cunningham (10.1016/S0167-7799(00)88997-0_bib6) 1994; 13 10.1016/S0167-7799(00)88997-0_bib7 10.1016/S0167-7799(00)88997-0_bib3 Balass (10.1016/S0167-7799(00)88997-0_bib12) 1993; 90 Hynes (10.1016/S0167-7799(00)88997-0_bib10) 1990; 29 McLafferty (10.1016/S0167-7799(00)88997-0_bib16) 1993; 128 Scott (10.1016/S0167-7799(00)88997-0_bib25) 1990; 249 10.1016/S0167-7799(00)88997-0_bib2 Creighton (10.1016/S0167-7799(00)88997-0_bib8) 1987; 52 Goodson (10.1016/S0167-7799(00)88997-0_bib13) 1994; 91 Dennis (10.1016/S0167-7799(00)88997-0_bib21) 1994; 269 Devlin (10.1016/S0167-7799(00)88997-0_bib26) 1990; 249 Koivunen (10.1016/S0167-7799(00)88997-0_bib20) 1995; 13 de (10.1016/S0167-7799(00)88997-0_bib11) 1992; 31 Meola (10.1016/S0167-7799(00)88997-0_bib31) 1995; 154 Brendt (10.1016/S0167-7799(00)88997-0_bib9) 1993; 234 Roberts (10.1016/S0167-7799(00)88997-0_bib28) 1992; 89 Parmley (10.1016/S0167-7799(00)88997-0_bib1) 1988; 73 Dennis (10.1016/S0167-7799(00)88997-0_bib22) 1994; 269 Pinilla (10.1016/S0167-7799(00)88997-0_bib15) 1993; 128 Clackson (10.1016/S0167-7799(00)88997-0_bib4) 1994; 12 Cwirla (10.1016/S0167-7799(00)88997-0_bib14) 1990; 87 Hoess (10.1016/S0167-7799(00)88997-0_bib17) 1994; 153 Folgori (10.1016/S0167-7799(00)88997-0_bib30) 1994; 13 Lane (10.1016/S0167-7799(00)88997-0_bib5) 1993; 5 Clackson (10.1016/S0167-7799(00)88997-0_bib23) 1995; 267 Smith (10.1016/S0167-7799(00)88997-0_bib29) 1993; 128 Feng (10.1016/S0167-7799(00)88997-0_bib24) 1994; 266 Kay (10.1016/S0167-7799(00)88997-0_bib27) 1993; 128 Koivunen (10.1016/S0167-7799(00)88997-0_bib19) 1994; 124 Leatherbarrow (10.1016/S0167-7799(00)88997-0_bib18) 1991; 30 |
| References_xml | – volume: 13 start-page: 265 year: 1995 end-page: 270 ident: bib20 publication-title: Bio/Technology – volume: 128 start-page: 71 year: 1993 end-page: 76 ident: bib15 publication-title: Gene – volume: 267 start-page: 383 year: 1995 end-page: 386 ident: bib23 publication-title: Science – volume: 30 start-page: 10717 year: 1991 end-page: 10721 ident: bib18 publication-title: Biochemistry – reference: Ladner, R. C., in – reference: Ladner, R. C., Guterman, S. K., Roberts, R. L., Markland, W., Ley, A. C. and Kent, R. B. (1993) – volume: 90 start-page: 10638 year: 1993 end-page: 10642 ident: bib12 publication-title: Proc. Natl Acad. Sci. USA – volume: 12 start-page: 173 year: 1994 end-page: 183 ident: bib4 publication-title: Trends Biotechnol. – volume: 269 start-page: 22137 year: 1994 end-page: 22144 ident: bib22 publication-title: J. Biol. Chem. – volume: 29 start-page: 10018 year: 1990 end-page: 10022 ident: bib10 publication-title: Biochemistry – volume: 128 start-page: 29 year: 1993 end-page: 36 ident: bib16 publication-title: Gene – volume: 124 start-page: 373 year: 1994 end-page: 380 ident: bib19 publication-title: J. Cell Biol. – volume: 89 start-page: 2429 year: 1992 end-page: 2433 ident: bib28 publication-title: Proc. Natl Acad. Sci. USA – volume: 154 start-page: 3162 year: 1995 end-page: 3172 ident: bib31 publication-title: J. Immunol. – volume: 5 start-page: 268 year: 1993 end-page: 271 ident: bib5 publication-title: Curr. Opin. Immunol. – reference: (Kay, B.,Winter, J. McCafferty, J., eds) Academic Press (in press). – volume: 31 start-page: 270 year: 1992 end-page: 279 ident: bib11 publication-title: Biochemistry – volume: 73 start-page: 305 year: 1988 end-page: 318 ident: bib1 publication-title: Gene – volume: 52 start-page: 511 year: 1987 end-page: 519 ident: bib8 publication-title: Cold Spring Harbor Symp. Quant. Biol. – reference: 5223409 – volume: 87 start-page: 6378 year: 1990 end-page: 6382 ident: bib14 publication-title: Proc. Natl Acad. Sci. USA – volume: 249 start-page: 404 year: 1990 end-page: 406 ident: bib26 publication-title: Science – volume: 128 start-page: 59 year: 1993 end-page: 65 ident: bib27 publication-title: Gene – volume: 266 start-page: 1241 year: 1994 end-page: 1247 ident: bib24 publication-title: Science – volume: 91 start-page: 7129 year: 1994 end-page: 7133 ident: bib13 publication-title: Proc. Natl Acad. Sci. USA – reference: Ladner, R. C. and Guterman, S. K. (1990) – reference: WO90/02809 – volume: 249 start-page: 386 year: 1990 end-page: 390 ident: bib25 publication-title: Science – volume: 234 start-page: 735 year: 1993 end-page: 750 ident: bib9 publication-title: J. Mol. Biol. – volume: 128 start-page: 37 year: 1993 end-page: 42 ident: bib29 publication-title: Gene – volume: 13 start-page: 2508 year: 1994 end-page: 2515 ident: bib6 publication-title: EMBO J. – volume: 269 start-page: 22129 year: 1994 end-page: 22136 ident: bib21 publication-title: J. Biol. Chem. – volume: 13 start-page: 2236 year: 1994 end-page: 2243 ident: bib30 publication-title: EMBO J. – volume: 153 start-page: 724 year: 1994 end-page: 729 ident: bib17 publication-title: J. Immunol. – volume: 30 start-page: 10717 year: 1991 ident: 10.1016/S0167-7799(00)88997-0_bib18 publication-title: Biochemistry doi: 10.1021/bi00108a016 – volume: 73 start-page: 305 year: 1988 ident: 10.1016/S0167-7799(00)88997-0_bib1 publication-title: Gene doi: 10.1016/0378-1119(88)90495-7 – volume: 154 start-page: 3162 year: 1995 ident: 10.1016/S0167-7799(00)88997-0_bib31 publication-title: J. Immunol. doi: 10.4049/jimmunol.154.7.3162 – volume: 89 start-page: 2429 year: 1992 ident: 10.1016/S0167-7799(00)88997-0_bib28 – volume: 90 start-page: 10638 year: 1993 ident: 10.1016/S0167-7799(00)88997-0_bib12 – ident: 10.1016/S0167-7799(00)88997-0_bib3 – volume: 29 start-page: 10018 year: 1990 ident: 10.1016/S0167-7799(00)88997-0_bib10 publication-title: Biochemistry doi: 10.1021/bi00495a002 – volume: 269 start-page: 22129 year: 1994 ident: 10.1016/S0167-7799(00)88997-0_bib21 publication-title: J. Biol. Chem. doi: 10.1016/S0021-9258(17)31765-9 – volume: 269 start-page: 22137 year: 1994 ident: 10.1016/S0167-7799(00)88997-0_bib22 publication-title: J. Biol. Chem. doi: 10.1016/S0021-9258(17)31766-0 – volume: 13 start-page: 2236 year: 1994 ident: 10.1016/S0167-7799(00)88997-0_bib30 publication-title: EMBO J. doi: 10.1002/j.1460-2075.1994.tb06501.x – volume: 124 start-page: 373 year: 1994 ident: 10.1016/S0167-7799(00)88997-0_bib19 publication-title: J. Cell Biol. doi: 10.1083/jcb.124.3.373 – volume: 13 start-page: 265 year: 1995 ident: 10.1016/S0167-7799(00)88997-0_bib20 publication-title: Bio/Technology doi: 10.1038/nbt0395-265 – volume: 249 start-page: 386 year: 1990 ident: 10.1016/S0167-7799(00)88997-0_bib25 publication-title: Science doi: 10.1126/science.1696028 – ident: 10.1016/S0167-7799(00)88997-0_bib7 – volume: 267 start-page: 383 year: 1995 ident: 10.1016/S0167-7799(00)88997-0_bib23 publication-title: Science doi: 10.1126/science.7529940 – volume: 12 start-page: 173 year: 1994 ident: 10.1016/S0167-7799(00)88997-0_bib4 publication-title: Trends Biotechnol. doi: 10.1016/0167-7799(94)90079-5 – volume: 5 start-page: 268 year: 1993 ident: 10.1016/S0167-7799(00)88997-0_bib5 publication-title: Curr. Opin. Immunol. doi: 10.1016/0952-7915(93)90016-L – volume: 128 start-page: 71 year: 1993 ident: 10.1016/S0167-7799(00)88997-0_bib15 publication-title: Gene doi: 10.1016/0378-1119(93)90155-V – volume: 234 start-page: 735 year: 1993 ident: 10.1016/S0167-7799(00)88997-0_bib9 publication-title: J. Mol. Biol. doi: 10.1006/jmbi.1993.1623 – volume: 13 start-page: 2508 year: 1994 ident: 10.1016/S0167-7799(00)88997-0_bib6 publication-title: EMBO J. doi: 10.1002/j.1460-2075.1994.tb06540.x – volume: 128 start-page: 29 year: 1993 ident: 10.1016/S0167-7799(00)88997-0_bib16 publication-title: Gene doi: 10.1016/0378-1119(93)90149-W – volume: 153 start-page: 724 year: 1994 ident: 10.1016/S0167-7799(00)88997-0_bib17 publication-title: J. Immunol. doi: 10.4049/jimmunol.153.2.724 – ident: 10.1016/S0167-7799(00)88997-0_bib2 – volume: 52 start-page: 511 year: 1987 ident: 10.1016/S0167-7799(00)88997-0_bib8 – volume: 91 start-page: 7129 year: 1994 ident: 10.1016/S0167-7799(00)88997-0_bib13 – volume: 128 start-page: 37 year: 1993 ident: 10.1016/S0167-7799(00)88997-0_bib29 publication-title: Gene doi: 10.1016/0378-1119(93)90150-2 – volume: 31 start-page: 270 year: 1992 ident: 10.1016/S0167-7799(00)88997-0_bib11 publication-title: Biochemistry doi: 10.1021/bi00116a037 – volume: 249 start-page: 404 year: 1990 ident: 10.1016/S0167-7799(00)88997-0_bib26 publication-title: Science doi: 10.1126/science.2143033 – volume: 128 start-page: 59 year: 1993 ident: 10.1016/S0167-7799(00)88997-0_bib27 publication-title: Gene doi: 10.1016/0378-1119(93)90153-T – volume: 87 start-page: 6378 year: 1990 ident: 10.1016/S0167-7799(00)88997-0_bib14 – volume: 266 start-page: 1241 year: 1994 ident: 10.1016/S0167-7799(00)88997-0_bib24 publication-title: Science doi: 10.1126/science.7526465 |
| SSID | ssj0003791 |
| Score | 1.8254324 |
| SecondaryResourceType | review_article |
| Snippet | Displaying proteins and peptides on genetic packages and selecting packages that display high-affinity binders allows large numbers of peptidyl compounds to be... |
| SourceID | proquest pubmed pascalfrancis crossref elsevier |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 426 |
| SubjectTerms | Amino Acid Sequence Aminoacids, peptides. Hormones. Neuropeptides Analytical, structural and metabolic biochemistry Biological and medical sciences Fundamental and applied biological sciences. Psychology Molecular Sequence Data Peptides - metabolism Protein Conformation Proteins |
| Title | Constrained peptides as binding entities |
| URI | https://dx.doi.org/10.1016/S0167-7799(00)88997-0 https://www.ncbi.nlm.nih.gov/pubmed/7546567 https://www.proquest.com/docview/15575678 https://www.proquest.com/docview/19886404 https://www.proquest.com/docview/77575950 |
| Volume | 13 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT-MwEB7xOMAKrZZHteWZAwc4hDrxKzmialF3KzjwENwsJ7GlSqhUtFz57cw4SYFDQdpTJMszdmYm47EyMx_AcYWGWxSJjWWldSyEtLEtMhkT0LFPmfNpSrXDl1dqcCf-PciHJei3tTCUVtn4_tqnB2_djPQaafYmo1HvhhLotUZvSpk6ucZ7-2rKc4WmvXr-dzi4mjtkrmvgPGrxTQTvhTw1kzB4wthp4BOzRUfUxsROUXC-RrxYHJKGo-niF_xsYsrovN72Jiy58Ras9Vsoty348aHr4DacEEhngIZwVTShrJbKTSM7jYpRKHGJ2j6rO3B38ee2P4gbwIS4FDKZxaV3FD8kymknhLeMS2e5zzEk8kXJrFUYbKVZlaOXs1QVmyqH06TFK6lAgfMOrIyfxu43RLmvuNLCIeNSZMxmPkm4K3xaeua9510QrYxM2XQTp50_mg9pY0obEq1hzATRGtaFsznZpG6n8R1B1irAfLILgy7_O9KDTwqbL8iVyplIunDUKtCgPuhHiR27p5epwRhLSzzFv5iRZ5kSTCyeoTVBn0rcRae2jfnymvDnld79_zfbg_VQWR9yCvdhZfb84g4wNpoVh7B89pocNl8APYfX98M3BTUIrw |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV07T8MwED4hGApCiKcozwwMMIQ6iR_JiCqqAoUFkNgsJ7GlSqhUtKz8du6cpNChILFa50fu7PNn5e4-gLMSN26eRyYUpVIh58KEJk9FSETHLmbWxTHlDt8_yP4zv30RL0vQbXJhKKyy9v2VT_feum7p1NrsjIfDziMF0CuF3pQidTKF7_YVjseXTufl53ecR6Iq2jwq8E3i32k81RC-8ZyxCz9KyBZdUOtjM0G1uYrvYjEg9RdTbxM2akQZXFWL3oIlO9qGVrchctuGtR81B3fgnCg6PTGELYMxxbSUdhKYSZAPfYJL0FRZ3YXn3vVTtx_WdAlhwUU0DQtnCT1E0irLuTMsEdYkLkNA5PKCGSMRasVpmaGSDOXExtKimDD4IOWo7mQPlkdvI7sPQebKRCpuceCCp8ykLooSm7u4cMw5l7SBNzrSRV1LnFb-qn8EjUmlSbWaMe1Vq1kbLmfdxlUxjb86pI0B9Nyu0Ojw_-p6PGew2YSJlBnjURtOGwNqtAf9JjEj-_Yx0YiwlMA7_BeJLE0lZ3yxhFJEfCpwFXvV3phNr4h9XqqD_3_ZKbT6T_cDPbh5uDuEVZ9j76MLj2B5-v5hjxElTfMTfwq-AOFfB9A |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Constrained+peptides+as+binding+entities&rft.jtitle=Trends+in+biotechnology+%28Regular+ed.%29&rft.au=Ladner%2C+R+C&rft.date=1995-10-01&rft.issn=0167-7799&rft.volume=13&rft.issue=10&rft.spage=426&rft_id=info:doi/10.1016%2FS0167-7799%2800%2988997-0&rft_id=info%3Apmid%2F7546567&rft.externalDocID=7546567 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0167-7799&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0167-7799&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0167-7799&client=summon |