Emerging functions of tissue-resident eosinophils

• Published in: The Journal of experimental medicine Vol. 220; no. 7
• Main Authors: Gurtner, Alessandra, Crepaz, Daniel, Arnold, Isabelle C.
• Format: Journal Article
• Language: English
• Published: United States Rockefeller University Press 03.07.2023
• Subjects: Cytokines; Eosinophils; Gastrointestinal Tract; Humans; Immune System Diseases; Mucosal Immunology; Review

Eosinophils are typically considered tissue-damaging effector cells in type 2 immune-related diseases. However, they are also increasingly recognized as important modulators of various homeostatic processes, suggesting they retain the ability to adapt their function to different tissue contexts. In...