Leukocyte telomere length, mitochondrial DNA copy number, and coronary artery disease risk and severity: A two-stage case-control study of 3064 Chinese subjects

• Published in: Atherosclerosis Vol. 284; pp. 165 - 172
• Main Authors: Wang, Xue-bin, Cui, Ning-hua, Zhang, Shuai, Liu, Ze-jin, Ma, Jun-fen, Ming, Liang
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.05.2019
• Subjects: Coronary artery disease; Leukocyte telomere length; Mitochondrial DNA copy number; Oxidative stress; Mitochondrial DNA copy number; Oxidative stress; Coronary artery disease; Leukocyte telomere length

Leukocyte telomere length (TL) and mitochondrial DNA copy number (mtDNA-CN), as hallmarks of cellular aging, may be involved in the development of coronary artery disease (CAD) by modulating oxidative stress. This study aimed to investigate the effects of leukocyte TL and mtDNA-CN alone or in combin...