Small fragments of hyaluronan are increased in individuals with obesity and contribute to low-grade inflammation through TLR-mediated activation of innate immune cells - Romo, Mònica; López-Vicario, Cristina; Pérez-Romero, Noelia; Casulleras, Mireia; Martínez-Puchol, Ana Isabel; Sánchez, Belén; Flores-Costa, Roger; Alcaraz-Quiles, José; Duran-Güell, Marta; Ibarzábal, Ainitze; Espert, Juan José; Clària, Joan; et al. (International Journal of Obesity, 2022)
Keywords: 13; 13/21; 38/39; 38/77; 631/443/319/1642/393; 692/699/2743/393; 82/80; 96/95; Adipose tissue; Body fat; Body mass index; Body size; Cell activation; Cytokines; Damage patterns; Enzyme-linked immunosorbent assay; Epidemiology; Extracellular matrix; Fluorescence; Fragments; Gene expression; Health Promotion and Disease Prevention; Hyaluronan synthase; Hyaluronic acid; Immune system; Immunoassay; Inflammation; Interleukin 8; Internal Medicine; Ion exchange; Ion-exchange chromatography; Leukocytes; Leukocytes (neutrophilic); Low molecular weights; Medicine; Medicine & Public Health; Metabolic Diseases; Molecular weight; Monocyte chemoattractant protein 1; Monocytes; NF-κB protein; Obesity; Peripheral blood mononuclear cells; Phosphorylation; Plasma levels; Proteins; Public Health; Statistical analysis; Toll-like receptors