The molecular virology of coronaviruses

• Published in: The Journal of biological chemistry Vol. 295; no. 37; pp. 12910 - 12934
• Main Authors: Hartenian, Ella, Nandakumar, Divya, Lari, Azra, Ly, Michael, Tucker, Jessica M., Glaunsinger, Britt A.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 11.09.2020; American Society for Biochemistry and Molecular Biology
• Subjects: Animals; Antigens, Viral - immunology; cellular immune response; coronavirus; Coronavirus - genetics; Coronavirus - immunology; Coronavirus - physiology; Coronavirus Infections - genetics; Coronavirus Infections - immunology; Coronavirus Infections - virology; endoplasmic reticulum; endoplasmic reticulum (ER); Gene Expression Regulation, Viral; Host-Pathogen Interactions; Humans; innate immunity; JBC Reviews; pathogenesis; plus-stranded RNA virus; RNA polymerase; SARS-CoV-2; viral replication; virology; virus; virus entry; Virus Physiological Phenomena; cellular immune response; coronavirus; RNA polymerase; virus; viral replication; pathogenesis; SARS-CoV-2; innate immunity; virology; plus-stranded RNA virus; virus entry; endoplasmic reticulum (ER); endoplasmic reticulum

Few human pathogens have been the focus of as much concentrated worldwide attention as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of COVID-19. Its emergence into the human population and ensuing pandemic came on the heels of severe acute respiratory syndrome coronavirus...